CompaniesRanked

2874 companies · fiscal year 2025 · SEC EDGAR · September 25, 2026

Largest healthcare companies by gross profit

Gross profit is revenue minus the direct cost of goods and services sold. Not every company reports it; those that do not are absent from this ranking. Figures are for fiscal year 2025 and are read directly from each company's SEC filings; the source column on every row links to the document.

Ranks 1–100 of 188 · Fiscal year 2025 · Data as of September 25, 2026

Johnson & Johnson (JNJ) tops the list with $63.9B in gross profit for fiscal 2025, ahead of AstraZeneca ($48.1B) and Novo Nordisk A S ($37.9B). The top 10 together report $306B in gross profit; the gap between #1 and #10 is ×4.50. 188 companies in Healthcare report gross profit, 12.3% of the 1524-filer universe. The last place on the list, Organogenesis Holdings, comes in at $366M.

Gross profit
#CompanyGross profitYoY15-year trend
1Johnson & JohnsonJNJUS$63.9B+4.2%
2AstraZenecaAZNGB$48.1B+9.7%
3Novo Nordisk A SNVODK$37.9B+6.2%
4GSKGSKGB$31.2B+9.3%
5Bristol Myers SquibbBMYUS$30.7B+70.2%
6CVS HealthCVSUS$28.5B−1.1%
7MedtronicMDTIE$20.9B+2.3%
8StrykerSYKUS$16.1B+11.3%
9McKessonMCKUS$14.6B+9.2%
10CenteneCNCUS$14.2B−16.8%
11Boston ScientificBSXUS$13.9B+20.6%
12BiogenBIIBUS$11.6B−6.3%
13CencoraCORUS$11.5B+15.8%
14Koninklijke PhilipsPHGNL$9.1B+8.2%
15Teva Pharmaceutical IndustriesTEVAIL$8.9B+10.8%
16GE Healthcare TechnologiesGEHCUS$8.2B+0.5%
17Cardinal HealthCAHUS$8.2B+10.2%
18Becton DickinsonBDXUS$7.6B−8.6%
19MedlineMDLNUS$7.5B+7.8%
20Intuitive SurgicalISRGUS$6.6B+17.9%
21Universe PharmaceuticalsUPCCN$6.3B+3.8%
22AlconALCUS$5.7B+4.2%
23Fresenius Medical CareFMSDE$5.6B−6.9%
24ViatrisVTRSUS$5.0B−10.8%
25Edwards LifesciencesEWUS$4.7B+9.5%
26Beone MedicinesONCCH$4.7B+45.3%
27SolventumSOLVUS$4.5B−3.1%
28Smith & NephewSNNGB$4.2B+3.6%
29Labcorp HoldingsLHUS$4.0B+10.7%
30HerbalifeHLFKY$3.9B+0.9%
31Quest DiagnosticsDGXUS$3.6B+35.1%
32Zimmer BiometZBHUS$3.4B+2.6%
33Baxter InternationalBAXUS$3.4B−15.2%
34OrganonOGNUS$3.3B−10.8%
35ResmedRMDUS$3.1B+15.1%
36DexcomDXCMUS$2.8B+14.9%
37United TherapeuticsUTHRUS$2.8B+9.0%
38Align TechnologyALGNUS$2.7B−3.1%
39Cooper CompaniesCOOUS$2.7B+3.3%
40Idexx LaboratoriesIDXXUS$2.7B+11.8%
41SterisSTEIE$2.6B+9.3%
42Elanco Animal HealthELANUS$2.6B+6.4%
43Molina HealthcareMOHUS$2.5B+7.6%
44Exact SciencesEXASUS$2.3B+17.9%
45InsuletPODDUS$1.9B+34.2%
46Dentsply SironaXRAYUS$1.8B−6.0%
47Hims & Hers HealthHIMSUS$1.7B+47.8%
48Minimed GroupMMEDUS$1.7B+9.9%
49Brightspring Health ServicesBTSGUS$1.5B+19.8%
50PerrigoPRGOIE$1.5B−3.1%
51Envista HoldingsNVSTUS$1.5B+8.3%
52EnovisENOVUS$1.3B+13.9%
53QiagenQGENNL$1.3B+34.3%
54TeleflexTFXUS$1.1B+8.0%
55Amneal PharmaceuticalsAMRXUS$1.1B+9.1%
56West Pharmaceutical ServicesWSTUS$1.1B+10.6%
57Option Care HealthOPCHUS$1.1B+7.4%
58Nu Skin EnterprisesNUSUS$1.0B−12.7%
59Globus MedicalGMEDUS$1.0B+34.4%
60Indivior PharmaceuticalsINDVUS$994M+3.9%
61PenumbraPENUS$942M+24.8%
62Lantheus HoldingsLNTHUS$942M−4.7%
63LivanovaLIVNGB$940M+10.1%
64Msa SafetyMSAUS$871M+1.2%
65Integra LifesciencesIARTUS$851M−10.7%
66Brookdale Senior LivingBKDUS$838M+4.8%
67Icu MedicalICUIUS$822M−0.3%
68Aveanna HealthcareAVAHUS$810M+27.5%
69Bio-TechneTECHUS$790M+2.7%
70HaemoneticsHAEUS$788M+5.2%
71Inspire Medical SystemsINSPUS$779M+14.6%
72ConmedCNMDUS$750M+2.4%
73Merit Medical SystemsMMSIUS$738M+14.8%
74Usana Health SciencesUSNAUS$724M+4.5%
75Trulieve CannabisTRLVUS$711M−0.6%
76Ascendis PharmaASNDDK$706M+104.4%
77Bright Horizons Family SolutionsBFAMUS$697M+12.5%
78Acadia PharmaceuticalsACADUS$685M+35.1%
79EmbectaEMBCUS$677M−7.9%
80Harmony BiosciencesHRMYUS$670M+20.1%
81Sotera HealthSHCUS$646M+7.2%
82Curaleaf HoldingsCURLFUS$631M−1.5%
83Prestige Consumer HealthcarePBHUS$596M−6.1%
84Myriad GeneticsMYGNUS$577M−1.5%
85Orthofix MedicalOFIXUS$566M+3.7%
86Tandem Diabetes CareTNDMUS$546M+11.5%
87Alphatec HoldingsATECUS$532M+25.4%
88Irhythm HoldingsIRTCUS$527M+29.4%
89Integer HoldingsITGRUS$500M+9.0%
90NovocureNVCR$488M+4.4%
91Warby ParkerWRBYUS$471M+10.2%
92Collegium PharmaceuticalCOLLUS$463M+22.8%
93Addus HomecareADUSUS$462M+23.2%
94Telix PharmaceuticalsTLXAU$426M+26.9%
95NeogenNEOGUS$409M−3.1%
96AtricureATRCUS$401M+15.3%
97Phibro Animal HealthPAHCUS$400M+27.7%
98Stevanato GroupSTVNIT$389M+18.7%
99BioventusBVSUS$388M−0.0%
100Organogenesis HoldingsORGOUS$366M+12.1%

All figures from SEC filings · FY2025 · 100

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<p style="max-width:680px;font:13px system-ui,sans-serif">Source: <a href="https://companiesranked.com/en/largest-healthcare-companies-by-gross-profit">Largest healthcare companies by gross profit</a> — CompaniesRanked, compiled from SEC EDGAR filings</p>

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{{cite web |title=Largest healthcare companies by gross profit |url=https://companiesranked.com/en/largest-healthcare-companies-by-gross-profit |website=CompaniesRanked |date=2026-09-25 |language=en}}

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CompaniesRanked. (September 25, 2026). Largest healthcare companies by gross profit. CompaniesRanked. https://companiesranked.com/en/largest-healthcare-companies-by-gross-profit

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@misc{companiesranked-en-largest-healthcare-companies-by-gross-profit-2026,
  author       = {{CompaniesRanked}},
  title        = {{Largest healthcare companies by gross profit}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/largest-healthcare-companies-by-gross-profit}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

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