Largest companies in Ireland by gross profit

Gross profit is revenue minus the direct cost of goods and services sold. Not every company reports it; those that do not are absent from this ranking. Figures are for fiscal year 2025 and are read directly from each company's SEC filings; the source column on every row links to the document.

Ranks 1–12 of 12 · Fiscal year 2025 · Data as of September 25, 2026

Medtronic (MDT) tops the list with $20.9B in gross profit for fiscal 2025, ahead of PDD Holdings ($14.4B) and CRH Public ($13.5B). The top 10 together report $76.3B in gross profit; the gap between #1 and #10 is ×21.75. 12 companies in Ireland report gross profit, 0.8% of the 1524-filer universe. The last place on the list, Amarin, comes in at $121M.

Gross profit
#CompanyGross profitYoY15-year trend
1MedtronicMDTIEHealthcare$20.9B+2.3%
2PDD HoldingsPDDIETechnology$14.4B+47.1%
3CRH PublicCRHIEMaterials$13.5B+6.5%
4Johnson Controls InternationalJCIIEIndustrials$8.6B+6.4%
5TE ConnectivityTELIEIndustrials$6.1B+11.4%
6Smurfit WestRockSWIEMaterials$6.0B+44.1%
7SterisSTEIEHealthcare$2.6B+9.3%
8James Hardie IndustriesJHXIEMaterials$1.7B+14.9%
9PerrigoPRGOIEHealthcare$1.5B−3.1%
10AdientADNTIEConsumer discretionary$961M+3.6%
11DoleDOLEIEConsumer staples$714M−0.5%
12AmarinAMRNIEHealthcare$121M+48.5%

All figures from SEC filings · FY2025 · 12

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{{cite web |title=Largest companies in Ireland by gross profit |url=https://companiesranked.com/en/largest-companies-in-ireland-by-gross-profit |website=CompaniesRanked |date=2026-09-25 |language=en}}

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@misc{companiesranked-en-largest-companies-in-ireland-by-gross-profit-2026,
  author       = {{CompaniesRanked}},
  title        = {{Largest companies in Ireland by gross profit}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/largest-companies-in-ireland-by-gross-profit}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

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