Healthcare companies with the highest operating cash flow

Operating cash flow is the cash the business itself produced over the year, before anything is spent on new assets or paid out to lenders and shareholders. It strips out the non-cash charges that separate profit from cash. Figures are for fiscal year 2025 and are read directly from each company's SEC filings; the source column on every row links to the document.

Ranks 1–100 of 244 · Fiscal year 2025 · Data as of September 25, 2026

Johnson & Johnson (JNJ) tops the list with $24.5B in operating cash flow for fiscal 2025, ahead of UnitedHealth Group ($19.7B) and AbbVie ($19.0B). The top 10 together report $168B in operating cash flow; the gap between #1 and #10 is ×2.10. 244 companies in Healthcare report operating cash flow, 9.7% of the 2517-filer universe. The last place on the list, Herbalife, comes in at $333M.

Operating cash flow
#CompanyOperating cash flowYoY15-year trend
1Johnson & JohnsonJNJUS$24.5B+1.1%
2UnitedHealth GroupUNHUS$19.7B−18.6%
3AbbVieABBVUS$19.0B+1.2%
4Novo Nordisk A SNVODK$18.0B+2.7%
5Eli LillyLLYUS$16.8B+90.7%
6MerckMRKUS$16.5B−23.3%
7AstraZenecaAZNGB$14.6B+22.9%
8Bristol Myers SquibbBMYUS$14.2B−6.8%
9HCA HealthcareHCAUS$12.6B+20.2%
10PfizerPFEUS$11.7B−8.2%
11CVS HealthCVSUS$10.6B+16.8%
12GSKGSKGB$10.2B+21.8%
13Gilead SciencesGILDUS$10.0B−7.5%
14AmgenAMGNUS$10.0B−13.3%
15Cigna GroupCIUS$9.6B−7.4%
16Abbott LaboratoriesABTUS$9.6B+11.8%
17MedtronicMDTIE$7.3B+4.1%
18McKessonMCKUS$6.2B+1.2%
19CenteneCNCUS$5.1B+3,203.9%
20StrykerSYKUS$5.0B+18.9%
21Regeneron PharmaceuticalsREGNUS$5.0B+12.6%
22Principal FinancialPFGUS$4.5B−1.4%
23Boston ScientificBSXUS$4.5B+32.0%
24Elevance HealthELVUS$4.3B−26.1%
25CencoraCORUS$3.9B+11.2%
26Vertex PharmaceuticalsVRTXUS$3.6B+$4.1B
27Tenet HealthcareTHCUS$3.5B+72.9%
28Becton DickinsonBDXUS$3.4B−10.8%
29Intuitive SurgicalISRGUS$3.0B+25.5%
30Fresenius Medical CareFMSDE$3.0B+17.3%
31ZoetisZTSUS$2.9B−1.7%
32IQVIA HoldingsIQVUS$2.7B−2.3%
33AflacAFLUS$2.6B−5.6%
34Royalty PharmaRPRXUS$2.5B−10.1%
35Cardinal HealthCAHUS$2.4B−36.3%
36ViatrisVTRSUS$2.3B+0.6%
373MMMMUS$2.3B+26.8%
38AlconALCUS$2.3B+9.3%
39BiogenBIIBUS$2.2B−23.3%
40GE Healthcare TechnologiesGEHCUS$2.0B+1.6%
41DavitaDVAUS$1.9B−6.7%
42Quest DiagnosticsDGXUS$1.9B+41.4%
43Universal Health ServicesUHSUS$1.9B−9.8%
44ResmedRMDUS$1.8B+25.0%
45MedlineMDLNUS$1.7B−1.4%
46Zimmer BiometZBHUS$1.7B+13.2%
47Teva Pharmaceutical IndustriesTEVAIL$1.6B+32.2%
48Labcorp HoldingsLHUS$1.6B+3.4%
49Edwards LifesciencesEWUS$1.6B+194.2%
50United TherapeuticsUTHRUS$1.6B+17.6%
51DexcomDXCMUS$1.4B+45.6%
52IncyteINCYUS$1.4B+321.5%
53Bausch Health CompaniesBHCCA$1.4B−12.3%
54Jazz PharmaceuticalsJAZZIE$1.4B−2.9%
55SterisSTEIE$1.3B+16.8%
56Smith & NephewSNNGB$1.3B+30.2%
57GenmabGMABDK$1.2B+5.3%
58Idexx LaboratoriesIDXXUS$1.2B+27.2%
59Encompass HealthEHCUS$1.2B+17.2%
60Beone MedicinesONCCH$1.1B+$1.3B
61Oscar HealthOSCRUS$1.1B+11.9%
62IconICLRIE$1.0B−19.5%
63HumanaHUMUS$921M−68.9%
64ExelixisEXELUS$884M+26.3%
65Baxter InternationalBAXUS$845M−17.1%
66Biomarin PharmaceuticalBMRNUS$828M+44.5%
67Cooper CompaniesCOOUS$796M+12.2%
68Neurocrine BiosciencesNBIXUS$783M+31.5%
69West Pharmaceutical ServicesWSTUS$755M+15.5%
70Globus MedicalGMEDUS$753M+44.7%
71Charles River Laboratories InternationalCRLUS$738M+0.4%
72Medpace HoldingsMEDPUS$713M+17.1%
73PTC TherapeuticsPTCTUS$711M+$819M
74OrganonOGNUS$700M−25.5%
75Unum GroupUNMUS$688M−54.6%
76Cno FinancialCNOUS$676M+7.6%
77QiagenQGENNL$654M−2.9%
78Halozyme TherapeuticsHALOUS$652M+36.0%
79AdapthealthAHCOUS$602M+11.1%
80Align TechnologyALGNUS$593M−19.6%
81InsuletPODDUS$569M+32.3%
82Ensign GroupENSGUS$564M+62.5%
83Elanco Animal HealthELANUS$560M+3.5%
84Community Health SystemsCYHUS$543M+13.1%
85Alnylam PharmaceuticalsALNYUS$524M+$532M
86AlkermesALKSIE$521M+18.6%
87BiontechBNTXDE$515M+129.2%
88Exact SciencesEXASUS$491M+133.4%
89Brightspring Health ServicesBTSGUS$490M+1,961.8%
90Ardent HealthARDTUS$471M+49.4%
91Pacs GroupPACSUS$404M+10.0%
92Lantheus HoldingsLNTHUS$390M−28.4%
93ChemedCHEUS$388M−7.0%
94SolventumSOLVUS$369M−68.9%
95Msa SafetyMSAUS$364M+22.8%
96Bright Horizons Family SolutionsBFAMUS$351M+3.9%
97Harmony BiosciencesHRMYUS$348M+58.4%
98Biocryst PharmaceuticalsBCRXUS$347M+$399M
99Amneal PharmaceuticalsAMRXUS$340M+15.2%
100HerbalifeHLFKY$333M+16.8%

All figures from SEC filings · FY2025 · 100

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{{cite web |title=Healthcare companies with the highest operating cash flow |url=https://companiesranked.com/en/healthcare-companies-with-the-highest-operating-cash-flow |website=CompaniesRanked |date=2026-09-25 |language=en}}

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@misc{companiesranked-en-healthcare-companies-with-the-highest-operating-cash-flow-2026,
  author       = {{CompaniesRanked}},
  title        = {{Healthcare companies with the highest operating cash flow}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/healthcare-companies-with-the-highest-operating-cash-flow}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

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