CompaniesRanked

2874 companies · fiscal year 2025 · SEC EDGAR · September 25, 2026

Healthcare companies with the highest profit margin

Net margin is net income divided by revenue. Only companies with at least $1 billion in revenue are ranked here: a small company can post an extreme margin that tells you nothing. Figures are for fiscal year 2025 and are read directly from each company's SEC filings; the source column on every row links to the document.

Ranks 1–100 of 122 · Fiscal year 2025 · Data as of September 25, 2026

Only companies with at least $1bn in revenue are ranked.

United Therapeutics (UTHR) tops the list with 41.9% in net margin for fiscal 2025, ahead of PTC Therapeutics (39.5%) and Novavax (39.2%). Across the top 10, net margin ranges from 41.9% down to 31.4%. 122 companies in Healthcare report net margin, 8.5% of the 1438-filer universe. The last place on the list, Elevance Health, comes in at 2.8%.

Net margin
#CompanyNet marginYoY15-year trend
1United TherapeuticsUTHRUS41.9%+1.0%
2PTC TherapeuticsPTCTUS39.5%+84.5 pp
3NovavaxNVAXUS39.2%+66.7 pp
4Acadia PharmaceuticalsACADUS36.5%+54.6%
5ExelixisEXELUS33.7%+40.3%
6Novo Nordisk A SNVODK33.1%−4.7%
7Vertex PharmaceuticalsVRTXUS32.9%+37.8 pp
8Royalty PharmaRPRXUS32.4%−14.6%
9Eli LillyLLYUS31.7%+34.7%
10Regeneron PharmaceuticalsREGNUS31.4%+1.1%
11Gilead SciencesGILDUS28.9%+1,631.4%
12Lakefront BiotherapeuticsLKFTBE28.9%+7.3%
13Johnson & JohnsonJNJUS28.5%+79.7%
14Intuitive SurgicalISRGUS28.4%+2.0%
15ZoetisZTSUS28.2%+5.1%
16MerckMRKUS28.1%+5.3%
17ResmedRMDUS27.2%+24.9%
18GenmabGMABDK25.9%−28.7%
19IncyteINCYUS25.0%+3,156.0%
20Idexx LaboratoriesIDXXUS24.6%+8.1%
21Halozyme TherapeuticsHALOUS22.7%−48.1%
22AflacAFLUS21.2%−26.1%
23AmgenAMGNUS21.0%+71.5%
24QiagenQGENNL20.3%+381.1%
25SolventumSOLVUS18.7%+222.1%
26Globus MedicalGMEDUS18.3%+347.7%
27DexcomDXCMUS17.9%+25.6%
28Medpace HoldingsMEDPUS17.8%−7.0%
29Edwards LifesciencesEWUS17.7%−76.9%
30GSKGSKGB17.5%+113.2%
31Prestige Consumer HealthcarePBHUS17.5%−7.3%
32AstraZenecaAZNGB17.4%+33.8%
33Indivior PharmaceuticalsINDVUS16.9%+2,776.5%
34Neurocrine BiosciencesNBIXUS16.7%+15.5%
35AlkermesALKSIE16.4%−30.5%
36West Pharmaceutical ServicesWSTUS16.1%−5.7%
37Lantheus HoldingsLNTHUS15.2%−25.6%
38Msa SafetyMSAUS14.9%−5.6%
39Abbott LaboratoriesABTUS14.7%−53.9%
40Bristol Myers SquibbBMYUS14.6%+33.2 pp
41Boston ScientificBSXUS14.4%+30.7%
42MedtronicMDTIE13.2%−5.0%
43SterisSTEIE13.2%+17.1%
44BiogenBIIBUS13.1%−22.5%
453MMMMUS13.0%−23.3%
46StrykerSYKUS12.9%−2.4%
47PenumbraPENUS12.7%+979.2%
48PfizerPFEUS12.4%−1.6%
49Stevanato GroupSTVNIT11.8%+10.5%
50Tenet HealthcareTHCUS11.1%−43.5%
51Biomarin PharmaceuticalBMRNUS10.8%−27.6%
52Nu Skin EnterprisesNUSUS10.8%+19.3 pp
53Align TechnologyALGNUS10.2%−3.5%
54Smith & NephewSNNGB10.1%+43.0%
55GE Healthcare TechnologiesGEHCUS10.1%−0.3%
56Encompass HealthEHCUS9.5%+12.5%
57AlconALCUS9.4%−8.3%
58Cooper CompaniesCOOUS9.2%−9.0%
59InsuletPODDUS9.1%−54.8%
60Quest DiagnosticsDGXUS9.0%+1.9%
61HCA HealthcareHCAUS9.0%+10.0%
62EmbectaEMBCUS8.8%+26.7%
63Pediatrix MedicalMDUS8.6%+13.6 pp
64Universal Health ServicesUHSUS8.6%+18.8%
65Zimmer BiometZBHUS8.6%−27.2%
66Merit Medical SystemsMMSIUS8.5%−4.5%
67Alnylam PharmaceuticalsALNYUS8.4%+20.8 pp
68IQVIA HoldingsIQVUS8.3%−6.4%
69Teva Pharmaceutical IndustriesTEVAIL8.2%+18.1 pp
70Principal FinancialPFGUS8.0%−18.9%
71National HealthcareNHCUS7.9%+1.4%
72DavitaDVAUS7.9%−19.0%
73Concentra Group Holdings ParentCONUS7.7%−12.2%
74Becton DickinsonBDXUS7.7%−9.1%
75AbbVieABBVUS6.9%−9.0%
76Ensign GroupENSGUS6.8%−2.8%
77Addus HomecareADUSUS6.7%+5.8%
78Sotera HealthSHCUS6.7%+66.0%
79Bright Horizons Family SolutionsBFAMUS6.6%+26.1%
80Labcorp HoldingsLHUS6.3%+9.6%
81Bio-TechneTECHUS6.0%−58.5%
82Unum GroupUNMUS5.6%−59.1%
83Integer HoldingsITGRUS5.5%−20.6%
84Hims & Hers HealthHIMSUS5.5%−35.9%
85Beone MedicinesONCCH5.4%+22.3 pp
86Cno FinancialCNOUS5.1%−46.0%
87Koninklijke PhilipsPHGNL5.0%+8.9 pp
88Fresenius Medical CareFMSDE5.0%+79.2%
89ProgynyPGNYUS4.5%−2.4%
90HerbalifeHLFKY4.5%−11.0%
91Community Health SystemsCYHUS4.1%+8.2 pp
92MedlineMDLNUS4.1%−10.8%
93Phibro Animal HealthPAHCUS3.7%+1,468.4%
94Option Care HealthOPCHUS3.7%−13.3%
95Pacs GroupPACSUS3.6%+165.6%
96ConmedCNMDUS3.4%−66.2%
97Guardian Pharmacy ServicesGRDNUS3.4%+12.4 pp
98Healthcare ServicesHCSGUS3.2%+39.7%
99OrganonOGNUS3.0%−77.7%
100Elevance HealthELVUS2.8%−15.8%

All figures from SEC filings · FY2025 · 100

see sources

Download this data as a CSV →

Embed this table

Free to use on any site. The table updates itself whenever the data is rebuilt — you paste it once. The only condition is that you keep the credit line below the table, so readers can reach the source.

<iframe src="https://companiesranked.com/embed/en/healthcare-companies-with-the-highest-profit-margin" title="Healthcare companies with the highest profit margin" width="100%" height="478" loading="lazy" style="max-width:680px;border:1px solid #e5e2dc;border-radius:6px"></iframe>
<p style="max-width:680px;font:13px system-ui,sans-serif">Source: <a href="https://companiesranked.com/en/healthcare-companies-with-the-highest-profit-margin">Healthcare companies with the highest profit margin</a> — CompaniesRanked, compiled from SEC EDGAR filings</p>

Open the embed on its own →

Cite this page

Ready-made references for the figures on this page, as published on September 25, 2026.

Wikipedia

{{cite web |title=Healthcare companies with the highest profit margin |url=https://companiesranked.com/en/healthcare-companies-with-the-highest-profit-margin |website=CompaniesRanked |date=2026-09-25 |language=en}}

APA 7

CompaniesRanked. (September 25, 2026). Healthcare companies with the highest profit margin. CompaniesRanked. https://companiesranked.com/en/healthcare-companies-with-the-highest-profit-margin

BibTeX

@misc{companiesranked-en-healthcare-companies-with-the-highest-profit-margin-2026,
  author       = {{CompaniesRanked}},
  title        = {{Healthcare companies with the highest profit margin}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/healthcare-companies-with-the-highest-profit-margin}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

The figures are rebuilt with every data refresh, so the reference carries the publication date. Add your own access date if your style requires one.

Companies with the highest profit margin →

By sector

By country